Medical treatment of vertebral osteoporosis

Medical treatment of osteoporosis--increasing options.

INTRODUCTION Many drugs are now available for the prevention and treatment of osteoporosis. They have differing levels of evidence of efficacy and each may be used according to clinical indications. METHODS A Medline search of clinical drug trials using various therapeutic agents used for osteoporosis was carried out. RESULTS Several randomised controlled trials have been carried out using ...

[Compression vertebral fracture in osteoporosis--prevention and treatment].

Vertebral fractures are the earliest and most common osteoporotic fractures. Usually vertebral fractures are associated with following clinical symptoms: back pain, posture change, loss of height, functional impairment, disability and decreasing quality of life. After 3 years of treatment raloxifene reduced the risk of first vertebral fracture by 55%. The fracture risk within one year was reduc...

Osteoporosis associated vertebral fractures—Health economic implications

INTRODUCTION Osteoporosis-associated vertebral fractures represent an increasing clinical and public health problem, one with important socioeconomic effects within western countries. The purpose of this study was to analyse demographic, medical, gender and socioeconomic aspects of osteoporotic vertebral fractures of the thoracic or lumbar spine over a period of at least 10-years. MATERIAL AN...

Title VERTEBRAL OSTEOPOROSIS ESPECIALLY ITS ROENTGENOLOGICAL STUDY

The efficacy and safety of vertebral fracture prevention therapies in post-menopausal osteoporosis treatment

OBJECTIVES Osteoporosis has become an increasing concern for older people as it may potentially lead to osteoporotic fractures. This study is designed to assess the efficacy and safety of ten therapies for post-menopausal women using network meta-analysis. METHODS We conducted a systematic search in several databases, including PubMed and Embase. A random-effects model was employed and result...